Afoxolaner 1093861-60-9 Organochlorine tshuaj tua kab mob Anti-Parasitics
Khoom npe:Afoxolaner
Synonyms:1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(( 2,2,2-trifluoroethyl) amino]ethyl]-
CAS Nr:.1093861-60-9
Zoo:hauv tsev
Molecular Formula:C26H17ClF9N3O3
Formula Luj:625.87 ib
Kev piav qhia
Afoxolaner yog ib qho systemictshuaj tua kabthiabacaricideuas yog muab los ntawm qhov ncauj los yog topically.
Afoxolaner inhibits kev loj hlobγ-aminobutyric acid(GABA)-gated chloride raws (GABAA receptors) thiab L-glutamate-gated chloride raws (GluCls).Potency ntawm Afoxolaner yog piv raufipronil.
Nws yog ib qho tshuaj tua kab dav dav nrog cov tshuaj tua kab zoo tiv thaiv cov zuam, hma, nab, hemiptera thiab diptera, thiab nws cov kab mob siab dua los yog piv rau cov tshuaj tua kab uas nquag siv.
Clinically qhia tau hais tias Afoxolaner tuaj yeem muab 12 lub lis piam tiv thaiv ntev rau dev rau cov tshuaj tiv thaiv kab mob ectoparasite.Nws yog qhov yooj yim dua thiab ua haujlwm zoo rau ob qho tib si tsiaj thiab tus tswv tsev.
Nws tuaj yeem tshem tawm thiab tua hma rau dev.Nws tuaj yeem siv tau sai sai rau cov neeg laus dev thiab kav ntev.Nws tseem tuaj yeem tiv thaiv fleas los ntawm kev nkag mus rau lub qe, yog li ua rau lub neej voj voog ntawm fleas.Cov tsiaj ectoparasites no nqus cov tsiaj noj, thiab tseem tuaj yeem kis tau ntau yam kab mob, xws li kab mob hlawv, kab mob Lyme, hav zoov encephalitis, thiab lwm yam. Nws yuav tsis tsuas yog cuam tshuam rau kev loj hlob thiab kev noj qab haus huv ntawm cov tsiaj, tab sis kuj yuav ua rau muaj kev phom sij rau tus tswv tsiaj.Afoxolaner tsis muaj kev ua si ntawm cov tsiaj txhu paj hlwb receptors, yog li nws muaj kev nyab xeeb heev rau cov tsiaj.
Afoxolaner yuav luag decomposed los ntawm cov tsiaj me.Thawj daim ntawv molecular nyob ib ncig ntawm 90-100% yog tawm los ntawm cov quav uas tsis muaj metabolites.Yuav luag tsis muaj lub raum tso tawm, kev nyab xeeb zoo heev, tsis muaj kev puas tsuaj rau lub siab thiab lub raum ntawm cov tsiaj me.
Nws tsis muaj kev paub txog tshuaj tiv thaiv thiab tshuaj tiv thaiv kev sib raug zoo, thiab tsis sib haum xeeb rau cov tshuaj tua kab uas twb muaj lawm.Tom qab kev tswj hwm qhov ncauj, cov tshuaj sib npaug ntawm lub cev.Nws yuav siv sij hawm 2 teev tom qab tswj qhov ncauj.Tom qab 4 teev, nws tuaj yeem tua tsawg kawg yog 80% ntawm cov kab.Lub sijhawm tiv thaiv tuaj yeem ncav cuag 12 lub lis piam.Rov qab kis kab mob tuaj yeem ua tiav cov tshuaj tua kab zoo heev.Nws yog ib hom tshuaj tiv thaiv kab mob ectoparasite nrog kev nyab xeeb siab, uas tsim nyog siv heev.
Specification (hauv tsev qauv)
| Yam khoom | Specification |
| Qhov tshwm sim | Dawb los yog tawm hmoov dawb |
| Kev txheeb xyuas | HNMR |
| LCMS | |
| Cov ntsiab lus dej | ≤ 1.0% |
| Tag nrho impurities | ≤ 2.0% |
| Purity | 98.0% ~ 100.0%, los ntawm HPLC |
Kev Them Nyiaj: T / T, L / C
Khoom Keeb Kwm: Tuam Tshoj
Chaw nres nkoj: Beijing / Shanghai / Hangzhou
Muaj peev xwm ntau lawm: 2kg / hli
Order (MOQ): 10g
Lub Sijhawm Lead: 3 Hnub Ua Haujlwm
Cia txias: Khaws rau hauv qhov chaw txias, qhuav, chav sov.
Pob khoom: vial, lub raj mis
Pob loj: 10g / vial, 50g / lub raj mis, 500g / lub raj mis
Cov ntaub ntawv kev nyab xeeb: Tsis yog cov khoom txaus ntshai
