Pimobendan 74150-27-9 Metabolism PDE inhibitor
Kev Them Nyiaj:T / T, L / C
Khoom Keeb Kwm:Tuam Tshoj
Shipping Chaw nres nkoj:Beijing / Shanghai / Hangzhou
Kev txiav txim (MOQ):1g ua
Lub Sijhawm Lead:3 hnub ua haujlwm
Muaj peev xwm ntau lawm:1 kg / hli
Kev cia khoom:Khaws rau hauv qhov chaw txias, qhuav, chav sov.
Cov khoom siv pob:vial, ua
Pob loj:1g / vial, 5 / vial, 10g / vial, 50g / lub raj mis, 500g / lub raj mis
Cov ntaub ntawv kev nyab xeeb:UN 2811 6.1/PG 3
Taw qhia
Pimobendan, yog ib qho tshuaj kho tsiaj.Nws yog calcium sensitizer thiab xaiv inhibitor ntawm phosphodiesterase 3 (PDE3) nrog cov teebmeem inotropic thiab vasodilator zoo.
Pimobendan yog siv los tswj lub plawv tsis ua hauj lwm hauv dev, feem ntau tshwm sim los ntawm myxomatous mitral valve kab mob (tseem hu ua endocardiosis), los yog dilated cardiomyopathy.Kev tshawb fawb tau pom tias raws li kev kho mob monotherapy, pimobendan nce lub sijhawm muaj sia nyob thiab txhim kho lub neej zoo hauv cov neeg mob canine nrog lub plawv tsis ua haujlwm theem nrab rau cov kab mob mitral valve thaum piv nrog benazepril, ACE inhibitor.
Specification (USP43)
| Yam khoom | Specification |
| Qhov tshwm sim | Dawb los yog daj me ntsis hmoov, hygroscopic |
| Mp | Txog 242 ℃ |
| Solubility | Xyaum insoluble hauv dej, dawb soluble hauv dimethylformamide, me ntsis soluble hauv acetone thiab hauv methanil. |
| Kev txheeb xyuas | Infrared absorption spectrophotometric, Sib piv pimobendan CRS. |
| Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem sib raug rau cov qauv kev daws teeb meem, raws li tau txais hauv Organic Impurities test. | |
| Cov hlau hnyav | ≤10ppm |
| Granularity | P90 ≤ 25μm |
| Particle loj | 20-80 mesh |
| Cov kuab tshuaj residual | ≤ 500ppm |
| Dej | ≤ 1.0% |
| Assay | 98.0% ~ 102.0%. |
| Sulfated tshauv | ≤ 0.10% |
| Yam khoom (HPLC) | |
| impurity A | ≤ 0.10% |
| impurity B | ≤ 0.10% |
| Lwm yam impurity | ≤ 0.10% |
| Tag nrho impurity | ≤ 0.20% |
