Alprostadil 745-65-3 Hormone thiab endocrine
Kev Them Nyiaj:T / T, L / C
Khoom Keeb Kwm:Tuam Tshoj
Shipping Chaw nres nkoj:Beijing / Shanghai / Hangzhou
Muaj peev xwm ntau lawm:1 kg / hli
Order (MOQ): 1g
Lub Sijhawm Lead:3 Hnub Ua Haujlwm
Kev cia khoom:nrog lub hnab ntim dej khov rau kev thauj mus los, -20 ℃ rau kev khaws cia ntev
Cov khoom siv pob:vial, ua
Pob loj:1g / vial, 5 / vial, 10g / vial, 50g / lub raj mis, 500g / lub raj mis
Cov ntaub ntawv kev nyab xeeb:UN 2811 6.1/PG 3
Taw qhia
Alprostadil, tseem hu ua Prostaglandin E1 lossis PEG1.Nws yog dav nyob rau hauv lub cev ntawm biologically active tshuaj, raws li ib tug ntawm cov tsev neeg prostaglandin, nws yog ib tug lees paub endogenous physiologically active tshuaj.
Nws tuaj yeem siv ncaj qha rau ntawm cov leeg nqaij leeg, kom nthuav cov hlab ntsha thiab ua kom cov ntshav khiav, uas tuaj yeem txhim kho microcirculation perfusion.Nws tuaj yeem inhibit platelet aggregation thiab thromboxane A2 ntau lawm, nrog rau inhibits atherosclerosis, lipid plaque thiab kev tiv thaiv kab mob.
Nws kuj muaj cov teebmeem nram qab no: kom nthuav dav ntawm cov hlab ntsha me me thiab cov hlab ntsha coronary, txo qis peripheral vascular tsis kam thiab ntshav siab.Txhawm rau tiv thaiv platelet membrane uas tuaj yeem tiv thaiv thrombosis.Txhawm rau tiv thaiv ischemic myocardium, uas tuaj yeem txo qhov loj ntawm myocardial infarct.Nws siv los kho lub plawv tsis ua hauj lwm thiab.Nws muaj diuretic thiab lub raum-tiv thaiv muaj nuj nqi, raws li nyob rau hauv expansion ntawm lub raum cov hlab ntsha nyob rau hauv thiaj li yuav ua rau kom lub raum ntshav khiav.Thaum ua li no, nws tuaj yeem tshem tawm cov tsis muaj protein ntau nitrogen, thiab tswj cov sodium thiab dej sib npaug.
Nws 's clinically siv yog dav.Xws li rau cov teeb meem ntshav qab zib, kab mob plawv thiab mob plawv tsis ua haujlwm.Kuj tseem siv rau qhov xwm txheej zoo li kab mob hauv lub plawv muaj teeb meem nrog pulmonary hypertension, cerebral infarction thiab mob ntev arterial occlusive kab mob.Rau qee qhov xwm txheej xws li lag ntseg tam sim ntawd, retinal vein occlusion, kab mob siab kab mob siab lossis mob plab, nws kuj muaj nuj nqi.Nws tuaj yeem siv rau kev kho mob rau lwm yam kab mob xws li duodenal ulcer, mob raum tsis txaus thiab pancreatitis.Nws yog daim ntawv thov hauv kev hloov pauv hauv nruab nrog cev.Siv rau lwm yam kab mob xws li erectile kawg, ua hauj lwm induction thiab postpartum hemorrhage, femoral taub hau necrosis, lumbar disc herniation, postherpetic neuralgia thiab bronchial hawb pob.
Nws yuav tsum ceev faj siv rau cov neeg mob uas muaj kab mob xws li lub plawv tsis ua hauj lwm, glaucoma, peptic ulcer los yog interstitial pneumonia.Nrog rau cov nyhuv irritant rau cov leeg, yuav pom cov tsos mob ntawm o xws li liab, o, kub thiab mob, uas yuav ua rau phlebitis.Nws yuav tsum tsis txhob siv rau kev nyab xeeb thaum muaj xwm txheej tshwm sim.
Specification (USP43)
| Yam khoom | Specification |
| Qhov tshwm sim | Dawb los yog me ntsis yellowish crystalline hmoov |
| Kev txheeb xyuas | IR |
| Residue ntawm ignition | ≤ 0.5% |
| Kev txwv ntawm chromium | ≤ 0.002% |
| Txwv ntawm rhodium | ≤ 0.002% |
| Cov khoom muaj feem xyuam | Prostaglandin A1 ≤ 1.5% |
| Prostaglandin B1 ≤0.1% | |
| Ib qho txawv teb chaws prostaglandin impurity eluting ua ntej prostaglandin A1 ≤0.9% | |
| impurity ntawm tus txheeb ze tuav lub sij hawm 0.6, txheeb ze rau prostaglandin A1 ≤0.9% | |
| Qhov sib npaug ntawm cov impurities ntawm cov txheeb ze tuav lub sij hawm 2.0 thiab 2.3 ≤0.6% | |
| Lwm yam txawv teb chaws prostaglandin impurity eluting tom qab prostaglandin A1 ≤0.9% | |
| Tag nrho impurities ≤2.0% | |
| Kev txiav txim siab dej | ≤ 0.5% |
| Cov kuab tshuaj residual | Ethanol ≤5000ppm |
| Acetone ≤5000ppm | |
| Dichloromethane ≤600ppm | |
| N-Hexane ≤290ppm | |
| N-Heptane ≤5000ppm | |
| Ethyl acetate ≤5000ppm | |
| Assay (ntawm lub hauv paus anhydrous) | 95.0% ~ 105.0% |
