Khoom

Dorametin yog ib tiam tshiab macrolide antiparasitic tshuaj.Nws yog ib qho tshuaj tua kab mob avermectin uas tsim los ntawm fermentation ntawm ib hom tshiab ntawm Streptomyces avermitis nrog cyclohexamic acid ua ntej.Nws raug suav hais tias yog ib qho ntawm cov tshuaj tiv thaiv kab mob zoo tshaj plaws hauv tsev neeg avermectin.

Cov tshuaj tua kab ntawm Doramectin zoo ib yam li Ivermectin, uas tuaj yeem cuam tshuam kev sib kis ntawm cov hlab ntsha ntawm cov hlab ntsha thiab cov leeg, thiab ua rau cov kab tuag tes tuag taw thiab tuag ntawm tus tswv tsev.Txawm li cas los xij, vim muaj cov ntshav siab ntau ntawm doramectin hauv lub cev, kev tshem tawm qeeb qeeb dua, thiab kev saib xyuas lub sijhawm ua haujlwm tau ntev, yog li cov tshuaj tua kab zoo dua li Ivermectin.Vim tias tsis muaj kev tsis haum tshuaj thaum siv Doramectin, yog li nws muaj kev nyab xeeb dua los siv.Nws kuj tseem xav tias yog cov tshuaj uas tsis yog Ivermectin.

Nws yog siv rau kev kho mob thiab tswj cov kab mob hauv plab (mob plab thiab pulmonary nematodes), zuam thiab mange (thiab lwm yam ectoparasites).

Clinically qhia tias Doramectin muaj txiaj ntsig zoo rau nematodes hauv plab hnyuv ntawm npua.Raws li tsab ntawv ceeb toom, npua tau muab tshuaj intramuscularly ntawm koob tshuaj 0.3 mg / kg lub cev hnyav.Qhov hnyav nce ntawm cov kab mob sib kis thiab cov kab mob sib kis tau ntau dua li ntawm pawg tswj hwm ntawm 7, 14 thiab 21 hnub tom qab kev tswj hwm.Piv nrog rau pawg tswj hwm, cov kab mob tau 100% tshem tawm yam tsis muaj kev phiv.

Nws kuj qhia tau hais tias nyob rau hauv kev kho mob ntawm Sarcoptes scabies, muaj cov teebmeem zoo los ntawm suckling piglets mus sows.

Doramectin kuj muaj rau nees ua qhov ncauj, flavored, bioadhesive gel nyob rau hauv lub npe.

Doramectin tsis ruaj khov hauv qhov xwm txheej.Nws yog sai decomposed thiab inactivated nyob rau hauv tshav ntuj.Nws cov tshuaj residual yog tshuaj lom rau cov ntses thiab cov kab mob hauv dej.Yog li ntawd, yuav tsum xyuam xim rau kev tiv thaiv dej.